Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,981
Tocris Bioscience™ Pimonidazole
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Hypoxia detection reagent
| CAS | 70132-50-2 |
|---|---|
| Chemical Name or Material | α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C11H18N4O3 |
| Formula Weight | Observed MW: 254.29 |
| Assay Percent Range | >98% |
1,982
Tocris Bioscience™ Filipin III
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Polyene antibiotic; inhibits formation of pathological isoform of prion protein
1,983
Tocris Bioscience™ Dynasore
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CAS: 304448-55-3 Molecular Formula: C18H14N2O4
| CAS | 304448-55-3 |
|---|---|
| Molecular Formula | C18H14N2O4 |
1,984
Tocris Bioscience™ BAPTA AM
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CAS: 126150-97-8 Molecular Formula: C34H40N2O18
| CAS | 126150-97-8 |
|---|---|
| Molecular Formula | C34H40N2O18 |
1,985
Tocris Bioscience™ NMS 873
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Potent and selective p97 ATPase (VCP) allosteric inhibitor
| CAS | 1418013-75-8 |
|---|---|
| Chemical Name or Material | 3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C27H28N4O3S2 |
| Formula Weight | Observed MW: 520.67 |
| Assay Percent Range | >98% |
1,986
Tocris Bioscience™ ci-IP3/PM
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Small and Specialty Supplier Partner
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Caged inositol triphosphate
1,987
Tocris Bioscience™ Galunisertib
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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ALK4 and ALK5 (TGFβRI) inhibitor
| Target | TGF-beta Receptor Inhibitors |
|---|---|
| CAS | 700874-72-2 |
| Product Type | Inhibitor |
| Purity | 98% |
| Chemical Name or Material | 4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4 H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H19N5O |
| Formula Weight | 369.43 |
1,988
Tocris Bioscience™ 5-Ethynyl-2'-deoxyuridine
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Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry
1,989
Tocris Bioscience™ 5-Ethynyluridine
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Uridine analog, used for labeling RNA synthesis
1,990
Tocris Bioscience™ Baricitinib
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Highly potent JAK1 and JAK2 inhibitor; also inhibits JAK3 and Tyk2
1,991
Tocris Bioscience™ T3
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T3 synthesized to Ancillary Material Grade
| Target | Compounds for Stem Cell Differentiation |
|---|---|
| CAS | 6893-02-03. |
| Purity | 0.98 |
| Chemical Name or Material | O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine |
| Molecular Formula | C15H12I3NO4 |
1,992
Tocris Bioscience™ P-3FAX-Neu5Ac
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Sialic acid analog; sialyltransferase inhibitor
1,993
Tocris Bioscience™ Irbesartan
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Potent AT1 antagonist
1,994
Tocris Bioscience™ BAM 15
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Mitochondrial protonophore uncoupler
| Target | Oxidative Phosphorylation Inhibitors |
|---|---|
| CAS | 210302-17-3 |
| Purity | >98% |
| Chemical Name or Material | N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H10F2N6O |
| Formula Weight | 340.29 |
1,995
Tocris Bioscience™ DAPI
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Fluorescent DNA stain
| Target | Fluorescent DNA Stains |
|---|---|
| CAS | 28718-90-3 |
| Purity | 0.95 |
| Chemical Name or Material | 2-[4-(Aminoiminomethyl)phenyl]-1 H-Indole-6-carboximidamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H15N50.2 HCl |
| Formula Weight | 350.25 |